PENERAPAN GOOD MANUFACTURING PRACTICES (GMP) DALAM PRODUKSI GARAM KONSUMSI BERYODIUM DI UKM BRONDONG LAMONGAN

Implementation Status and Barriers of Good Manufacturing Practice (gmp) for Chinese Patent Medicine

Background: Safety, quality and effectiveness of Chinese patent medicine (CPM) are highly relevant to the manufacturing process. However, the level of manufacturing practice (GMP) for CPM as implemented in China is less reported in literatures. Therefore, the aim of this paper was to reveal the implementation status of GMP for CPM in China, in terms of implementation principle, implementation c...

The characterization of a cyclic-di-GMP (c-Di-GMP) pathway leads to a new tool for studying c-Di-GMP metabolic genes.

Second messengers play an integral role in regulating a wide variety of pathways in response to triggers from the extracellular milieu. The intracellular second messenger cyclic diguanylate (c-di-GMP) has been shown to regulate microbial adaptation to extracellular environments in myriad ways. Primarily studied in Gram-negative bacteria thus far, c-di-GMP regulates motility, biofilm formation, ...

Bacterial c-di-GMP Is an Immunostimulatory

Good Architecture = Good (ADL + Practices)

In order to ensure the quality of their software development, companies incorporate best practices from recognized repositories or from their own experiences. These best practices are often described in software quality manuals which does not guarantee their implementation. In this paper, we propose a framework for the implementation of best practices concerning the design of the software archi...

The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex

Streptomyces are ubiquitous soil bacteria that undergo a complex developmental transition coinciding with their production of antibiotics. This transition is controlled by binding of a novel tetrameric form of the second messenger, 3΄-5΄ cyclic diguanylic acid (c-di-GMP) to the master repressor, BldD. In all domains of life, nucleotide-based second messengers allow a rapid integration of extern...